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Are you talking about HDD encryption, and pre-boot encryption?
Guardian Edge, will do both. We had them in recently for a run down, as we're currently looking into some Endpoint security. I think Sophos also have a similar offering.
Steer clear of Safeboot/McAfee Endpoint Encryption if at all possible. Had a load of issues with it on our machines and all McAfee will say is 'it must be one of the other pieces of software on the machine conflicting, contact them'.